In recent years, it has been reported that fundus laser therapy can prevent retinal detachment in the later stages of CMVR and results in less damage and fewer complications ( 7- 9). Retinal reattachment is affected by many factors, and the therapeutic effect is generally unsatisfactory. Full-thickness retinal necrosis and retinal detachment caused by CMVR require complicated operations such as retinotomy, which is a necessary procedure during vitrectomy surgery. Research has shown that the incidence of retinal detachment is 50% 1 year after the diagnosis of CMVR ( 6). However, the most serious complication is retinal detachment, which generally has a devastating effect on the patient’s vision ( 4, 5). It directly damages the retina, the macular area, and the optic papilla, and can result in vision loss due to complications such as immune reconstitution uveitis, macular edema, or cataracts ( 4). Accepted for publication Feb 04, 2021.Ĭytomegalovirus retinitis (CMVR) is the main cause of vision loss in patients with acquired immunodeficiency syndrome (AIDS) ( 1- 3).

Keywords: Cytomegalovirus retinitis (CMVR) laser therapy retinal detachment therapeutic efficacy

The retinal pigment reaction was not obvious in 8 eyes.Ĭonclusions: The use of laser therapy in the main maintenance period of anti-CMV treatment can effectively reduce the incidence of retinal detachment in patients with AIDS and CMVR, and the therapy is safe and reliable. Intraocular pressure (IOP) increased in 3 eyes within 2 weeks of laser therapy. After laser therapy, 39.13% of patients exhibited keratic precipitates (KP), 30.43% had anterior chamber flare (±), 50% had anterior chamber flare (+), and 19.57% had anterior chamber flare (++). There was no significant difference between the two groups in the number of CD4 + T cells, the load of human immunodeficiency virus, or the time between the detachment and the end of the induction period. Results: The percentage of retinal detachment in the nonlaser group was 24% compared with 6.5% in the laser group (P=0.018). The safety of laser therapy was observed, and the efficacy of the therapy was determined by evaluating the incidence of retinal detachment. Both groups were followed up for 24 months.

The patients were randomly divided into a nonlaser group (50 eyes from 43 patients), who were treated with anti-CMV therapy, and a laser group (46 eyes from 37 patients), who were treated with a fundus laser method to close the retinopathy area after commencing the maintenance stage of anti-CMV treatment. Methods: A total of 96 eyes from 80 patients with AIDS and CMVR who received anticytomegalovirus (anti-CMV) treatment in the ophthalmology and infection centers of Beijing YouAn Hospital, between June 2016 and August 2018 were retrospectively investigated. Policy of Dealing with Allegations of Research Misconductīackground: The aim of the present study was to evaluate the clinical efficacy of laser therapy in the prevention of retinal detachment in patients with acquired immunodeficiency syndrome (AIDS) and cytomegalovirus retinitis (CMVR).Policy of Screening for Plagiarism Process.

Normal retina vs cmv retinitis